Maternal pelvic size, fetal growth and risk of stroke in adult offspring in a large Swedish cohort
2016 (English)In: Journal of Developmental Origins of Health and Disease, ISSN 2040-1744, E-ISSN 2040-1752, Vol. 7, no 1, 108-113 p.Article in journal (Refereed) Published
Earlier research suggests that maternal pelvic size is associated with offspring's stroke risk in later life. We followed 6362 men and women from Uppsala, Sweden, born between 1915 and 1929 from 1964 to 2008 to assess whether maternal pelvic size was associated with incidence of thrombotic stroke (TS), haemorrhagic stroke (HS) and other stroke (OS). Offspring whose mothers had a flat pelvis had lower birth weight and birth-weight-for-gestational-age compared with those who did not. Inverse linear associations of birth-weight-for-gestational-age were observed with TS and OS. Female offspring whose mothers had a flat pelvis had increased risk of TS, but flat pelvis was not associated with other types of stroke. A smaller difference between intercristal and interspinous diameters and a smaller external conjugate diameter were independently associated with HS, whereas no pelvic measurements were associated with OS. We conclude that a smaller pelvis in women may impact the health of their offspring in adulthood.
Place, publisher, year, edition, pages
2016. Vol. 7, no 1, 108-113 p.
childhood social class, fetal growth, pelvic size, stroke
Public Health, Global Health, Social Medicine and Epidemiology
IdentifiersURN: urn:nbn:se:su:diva-121852DOI: 10.1017/S2040174415007254ISI: 000367264300015PubMedID: 26441399OAI: oai:DiVA.org:su-121852DiVA: diva2:861820