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Application of CPPs for Brain Delivery
Stockholm University, Faculty of Science, Department of Neurochemistry.
Stockholm University, Faculty of Science, Department of Neurochemistry.
Stockholm University, Faculty of Science, Department of Neurochemistry. Tartu University, Estonia.
2015 (English)In: Cell-Penetrating Peptides: Methods and Protocols / [ed] Ülo Langel, Springer-Verlag New York, 2015, Vol. 1324, 349-356 p.Chapter in book (Refereed)
Abstract [en]

Cell-penetrating peptides provide a promising strategy for delivery of drugs across the blood-brain barrier. Here, we present an overview of CPP and peptide-mediated delivery to the central nervous system as well as a Transwell in vitro model to evaluate passage across an endothelial cell layer mimic of the blood-brain barrier.

Place, publisher, year, edition, pages
Springer-Verlag New York, 2015. Vol. 1324, 349-356 p.
Series
, Methods in Molecular Biology, ISSN 1064-3745 ; 1324
Keyword [en]
Blood–brain barrier, Transwell, Brain delivery, Glioblastoma, Cell-penetrating peptide
National Category
Biochemistry and Molecular Biology
Identifiers
URN: urn:nbn:se:su:diva-124909DOI: 10.1007/978-1-4939-2806-4_23ISI: 000376037700024PubMedID: 26202281ISBN: 978-1-4939-2805-7ISBN: 978-1-4939-2806-4OAI: oai:DiVA.org:su-124909DiVA: diva2:891236
Available from: 2016-01-06 Created: 2016-01-06 Last updated: 2016-06-20Bibliographically approved

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Srimanee, ArtitaRegberg, JakobLangel, Ülo
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