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No Significant Effect of Prefrontal tDCS on Working Memory Performance in Older Adults
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
Number of Authors: 3
2015 (English)In: Frontiers in Aging Neuroscience, ISSN 1663-4365, E-ISSN 1663-4365, Vol. 7, 230Article in journal (Refereed) Published
Abstract [en]

Transcranial direct current stimulation (tDCS) has been put forward as a non pharmacological alternative for alleviating cognitive decline in old age. Although results have shown some promise, little is known about the optimal stimulation parameters for modulation in the cognitive domain. In this study, the effects of tDCS over the dorsolateral prefrontal cortex (dIPFC) on working memory performance were investigated in thirty older adults. An N-back task assessed working memory before, during and after anodal tDCS at a current strength of 1 mA and 2 mA, in addition to sham stimulation. The study used a single-blind, cross-over design. The results revealed no significant effect of tDCS on accuracy or response times during or after stimulation, for any of the current strengths. These results suggest that a single session of tDCS over the dIPFC is unlikely to improve working memory, as assessed by an N-back task, in old age.

Place, publisher, year, edition, pages
2015. Vol. 7, 230
Keyword [en]
tDCS, working memory, plasticity, aging, N-back
National Category
Geriatrics Gerontology, specializing in Medical and Health Sciences Neurosciences
Identifiers
URN: urn:nbn:se:su:diva-126212DOI: 10.3389/fnagi.2015.00230ISI: 000366594600001PubMedID: 26696882OAI: oai:DiVA.org:su-126212DiVA: diva2:897729
Available from: 2016-01-26 Created: 2016-01-26 Last updated: 2016-01-26Bibliographically approved

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Frontiers in Aging Neuroscience
GeriatricsGerontology, specializing in Medical and Health SciencesNeurosciences

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ReferencesLink to record
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