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Cognitive behavioral treatments of obsessive-compulsive disorder. A systematic review and meta-analysis of studies published 1993-2014
Stockholm University, Faculty of Social Sciences, Department of Psychology. Karolinska Institutet, Sweden; University of Bergen, Norway; Haukeland University Hospital, Norway.
Number of Authors: 4
2015 (English)In: Clinical Psychology Review, ISSN 0272-7358, E-ISSN 1873-7811, Vol. 40, 156-169 p.Article, review/survey (Refereed) Published
Abstract [en]

Obsessive-compulsive disorder is ranked by the WHO as among the 10 most debilitating disorders and tends to be chronic without adequate treatment. The only psychological treatment that has been found effective is cognitive behavior therapy (CBT). This meta-analysis includes all RCTs (N = 37) of CBT for OCD using the interview-based Yale-Brown Obsessive Compulsive Scale, published 1993 to 2014. The effect sizes for comparisons of CBT with waiting-list (1.31), and placebo conditions (1.33) were very large, whereas those for comparisons between individual and group treatment (0.17), and exposure and response prevention vs. cognitive therapy (0.07) were small and non-significant. CBT was significantly better than antidepressant medication (0.55), but the combination of CBT and medication was not significantly better than CBT plus placebo (0.25). The RCTs have a number of methodological problems and recommendations for improving the methodological rigor are discussed as well as clinical implications of the findings.

Place, publisher, year, edition, pages
2015. Vol. 40, 156-169 p.
Keyword [en]
Obsessive-compulsive disorder, Exposure and response prevention, Cognitive therapy, Meta-analysis, Systematic review
National Category
Psychiatry Social and Clinical Pharmacy
URN: urn:nbn:se:su:diva-121177DOI: 10.1016/j.cpr.2015.06.003ISI: 000360254100012OAI: diva2:945521
Available from: 2016-07-01 Created: 2015-09-28 Last updated: 2016-07-01Bibliographically approved

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Öst, Lars-Göran
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