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Use of antidepressants in Parkinson's disease: A Swedish register-based study of over 1.5 million older people
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
Number of Authors: 3
2016 (English)In: Parkinsonism & Related Disorders, ISSN 1353-8020, E-ISSN 1873-5126, Vol. 27, 85-88 p.Article in journal (Refereed) Published
Abstract [en]

Introduction: It has been suggested that depression in Parkinson's Disease (PD) is often unrecognized and undertreated. However, few previous studies have studied the use of antidepressants in a large sample of both home-dwelling and institutionalized elderly persons with PD. We aimed to study the use of antidepressants in older persons using anti-parkinson drugs (APD, used as a proxy for PD), stratified by residential setting. Methods: We analyzed individual data on age, sex, residential setting and drug use in over 1.5 million older persons in the Swedish Prescribed Drug Register on 31th of December 2013. Results: Twenty-two percent of the home-dwellers and 50% of the institutionalized elderly persons with APD used antidepressants. Persons with APD had a higher probability of use of any antidepressant compared to persons without APD. A selective serotonin reuptake inhibitor (SSRI) was the most commonly used antidepressants in both settings followed by mirtazapin. Conclusions: The high use of antidepressants among older persons with APD warrants further studies on the quality of treatment of depression in PD.

Place, publisher, year, edition, pages
2016. Vol. 27, 85-88 p.
Keyword [en]
Antidepressants, Elderly, Parkinson's disease, Register-based research, Anti-parkinson drugs
National Category
Neurosciences Neurology
Identifiers
URN: urn:nbn:se:su:diva-132503DOI: 10.1016/j.parkreldis.2016.04.015ISI: 000378191800012PubMedID: 27117031OAI: oai:DiVA.org:su-132503DiVA: diva2:952998
Available from: 2016-08-16 Created: 2016-08-15 Last updated: 2016-08-16Bibliographically approved

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