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Well-being and immune response: a multi-system perspective
Stockholm University, Faculty of Social Sciences, Stress Research Institute. Karolinska Institutet, Sweden; University Hospital Essen, Germany.
2016 (English)In: Current opinion in pharmacology (Print), ISSN 1471-4892, E-ISSN 1471-4973, Vol. 29, 34-41 p.Article in journal (Refereed) Published
Abstract [en]

Whereas it is well-established that inflammation and other immune responses can change how we feel, most people are still surprised to hear that, conversely, well-being and its violations also affect our immune system. Here we show that those effects are highly adaptive and bear potential for both research and therapeutic applications. The studies discussed in this review demonstrate that immunity is tuned by ones emotions, personality, and social status as well as by other life style variables like sleep, nutrition, obesity, or exercise. We further provide a short excursion on the effects of stress and depression on immunity and discuss acute experimental endotoxemia as a model to study the effects of well-being on the innate immune response in humans.

Place, publisher, year, edition, pages
2016. Vol. 29, 34-41 p.
National Category
Pharmaceutical Sciences Psychology
Identifiers
URN: urn:nbn:se:su:diva-133849DOI: 10.1016/j.coph.2016.05.003ISI: 000382415200007PubMedID: 27318753Local ID: P-3359OAI: oai:DiVA.org:su-133849DiVA: diva2:971907
Available from: 2016-09-19 Created: 2016-09-19 Last updated: 2016-10-03Bibliographically approved

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