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Changes in DHEA-s levels during the first year of treatment in patients with clinical burnout are related to health development
Stockholm University, Faculty of Social Sciences, Stress Research Institute.
2016 (English)In: Biological Psychology, ISSN 0301-0511, E-ISSN 1873-6246, Vol. 120, 28-34 p.Article in journal (Refereed) Epub ahead of print
Abstract [en]

The regenerative hormone DHEA-S was measured in 122 patients with clinical burnout during their first year of treatment. Relations between change of DHEA-S levels and development in health were investigated. About half of the patients exhibited increased DHEA-S levels during the year, while the other half exhibited decreased levels. There was no difference in burnout symptoms or associated health status at baseline between subsequent DHEA-S increasing and DHEA-S decreasing groups. Greater reduction in the burnout symptoms was observed in patients in who DHEA-S levels increased during the year, than in the patients in who DHEA-S levels decreased. Relative change of DHEA-S and direction of the change during the year both predicted burnout symptoms at the end of the year. In addition, patients with increased DHEA-S levels had better self-rated health, vitality and well-being. Our data suggest that changes in DHEA-S are associated with prognosis for the outcome in burnout patients.

Place, publisher, year, edition, pages
2016. Vol. 120, 28-34 p.
Keyword [en]
Dehydroepiandrosterone sulfate, Changes in DHEA-S, Burnout, Health development
National Category
Medical and Health Sciences
URN: urn:nbn:se:su:diva-133851DOI: 10.1016/j.biopsycho.2016.08.003PubMedID: 27531310Local ID: P-3362OAI: diva2:971941
Available from: 2016-09-19 Created: 2016-09-19 Last updated: 2016-09-26

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Theorell, Töres
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