The Kunming-Montreal Global Biodiversity Framework marks a significant step toward conserving genetic diversity on a global scale. Sequencing advancements have broadened biodiversity studies by enabling the mapping of species distributions, increasing understanding of ecological interactions, and monitoring genetic diversity. However, these tools are hindered by inequalities and biases, particularly in biodiversity-rich developing countries. To navigate these challenges, we propose strategies using the existing biotechnological toolbox to make biodiversity data more accessible and useful for research and development. This includes increasing funding for database curation, improving metadata standards, addressing inequalities in technological capacity, and supporting holistic capacity-building programmes. Implementing these strategies can unlock new opportunities for biodiversity research aligned with sustainable development principles and can contribute to improved conservation outcomes.

Marine ecosystems host an extraordinary level of biodiversity, ranging from microscopic organisms to large marine species, each harboring unique genetic codes. The interconnection between marine biodiversity and human society forms a complex mosaic of social-ecological systems. At the core of these systems are marine genes and genomes that play diverse roles, from serving as sources for commercial products to being key elements in the climate regulation system. Despite their immense potential, significant gaps exist in understanding the value of marine genetics, their role within social-ecological systems, and how their use can ultimately contribute to biodiversity conservation efforts.

In this thesis, we first investigate how marine genes are currently used by biotechnology actors (Paper I). We then discuss the challenges biotechnology poses in biodiversity-rich developing countries and propose solutions to navigate these risks (Paper II). The findings offer insights for those interested in the nexus between equitable benefit-sharing, sustainable use of marine genetic resources, and ocean biodiversity conservation. Ultimately, this thesis aims not only to contribute to academic discourse but also to address the practical challenges of achieving the fair use of marine genetic resources amid rapid technological advances, insufficient data governance, and unprecedented threats to marine ecosystems.

Marine biotechnology is a rapidly growing sector of the ocean economy, but efforts to assess its value, and that of the genetic resources that enable it, remain contentious. Through a comprehensive literature review, we identified 67 distinct valuations of marine genetic resources. We analysed these using the IPBES Values Assessment typology and found a predominance of behaviour-based valuations using economic value indicators to assess monetary benefits from marine drug discovery.

Marine genetic resources hold great value for biotechnological innovation and sustainability-oriented research. However, studies indicate that intellectual property rights pertaining to these resources are concentrated in a handful of companies and countries, triggering contentious international debates. This paper highlights an overlooked dimension: the flow of scientific knowledge in the provision and use of marine genetic research. We identified 23,417 scientific studies that use marine genetic sequences, traced patent references to these studies, and revealed provider and user countries. We found that molecular biological research, oftentimes on bacterial species, attracted the most patenting interest. Some countries owned relatively more patents than they provided in science, with the U.S. benefiting the most from available research. Science by developing countries’ researchers saw limited uptake in patents. These findings aim to inform international biodiversity regimes, such as the UN Treaty on Biodiversity Beyond National Jurisdiction (BBNJ), on how to more equitably distribute marine genetic resources’ economic, socio-cultural, and ecological benefits.

Marine bioprospecting, which involves the exploration of genetic and biochemical material from marine organisms, can be used towards addressing a broad range of public and environmental health applications such as disease treatment, diagnostics and bioremediation. Marine genetic resources are important reservoirs for such bioprospecting efforts; however, the extent to which they are used commercially for natural product discovery and the marine sources from which they are derived are not well understood. Here we introduce a comprehensive database of marine genes referenced in patent filings, the Marine Bioprospecting Patent database. It includes 92,550 protein-coding sequences associated with 4,779 patent filings, identified by analysing all relevant records from genetic sequence databases. Three companies alone—BASF, IFF and DuPont—included sequences from 949 species (more than half of referenced species with identified marine origin). Microbial life in the deep sea, a vast and remote biome predominantly beyond national jurisdiction, is already attracting substantial economic interest; the top ten patent holders have all filed marine gene patents referencing sequences from deep-sea life. Our findings provide an updated understanding of the marine bioprospecting landscape, contribute to the sustainable use of marine biodiversity and underscore the need for policymakers to ensure stewardship of deep-sea ecosystems.

A central barrier to effective governance and accountability in fisheries is the limited transparency of corporate ownership. Transshipment—the transfer of catches, fuel, parts, or crew between fishing and cargo vessels known as reefers—is often criticized for its opacity and poor governance. Better insight into the beneficial ownership of vessels involved in transshipment and their operational patterns could lead to more effective management. Our study presents a publicly accessible database of reefers’ owners, operators, and flags. We identified 569 individual reefers and found that Russian and Chinese owners control 26 and 20% of the global reefer fleet, respectively. Results also show that 65% of all reefer vessels fly the flags of Russia, Panama, or China. This high level of consolidation suggests considerable leverage for enhancing transparency and governance. Our findings highlight the potential for reforming existing transshipment practices through collaboration among owners, flag states, fishery regulators, and scientists.