Open this publication in new window or tab >>2026 (English)In: Child and Adolescent Psychiatry and Mental Health, E-ISSN 1753-2000, Vol. 20, no 1, article id 92Article in journal (Refereed) Published
Abstract [en]
Background
Individuals with substance use problems have higher mortality risks than the general population. This study aimed to assess all-cause and specific-cause mortality among adolescents and young adults in specialized substance use treatment in Sweden, a largely overlooked group in the literature.
Methods
A registry cohort was compiled of patients (13–25 years) who between 2011 and 2021 were in contact with Sweden’s largest healthcare provider of adolescent substance use treatment, with mortality data covering the same period. Sex, migrant background, parental education, convictions and treatment variables were compiled from registries and included as predictors. We calculated crude mortality rates (CMRs) and estimated Cox regression models to explore the associations between the predictors and mortality. This also included testing for interactions between convictions and treatment variables.
Results
Among 23,709 patients, 229 deaths were recorded, meaning that slightly less than 1% died during the follow-up window. The overall CMR was 1.68 deaths per 1000 person years (95% CI = 1.47–1.91), with differences across some predictors. In the fully adjusted Cox regression, significantly elevated mortality risks were observed among males (HR = 1.69, 95%CI = 1.23–2.32), those who had received inpatient treatment (HR = 1.89, 95% CI = 1.42–2.52), and those who had been convicted (HR = 2.64, 95%CI = 1.92–3.63). No significant difference in mortality risk was observed for migrant status, parental education, or number of outpatient visits in the fully adjusted models. Among convicted patients, more outpatient visits were related to a lower mortality risk (HR = 0.98, 95%CI = 0.98–0.99), whereas inpatient treatment was associated with a higher mortality risk (HR = 2.14, 95%CI = 1.13–4.05).
Conclusions
Almost one out of hundred patients died during the follow-up period, greatly exceeding the mortality rate in adolescents and young adults in the general Swedish population. The mortality risk varied according to sex, treatment experiences, and convictions, but not according to migrant background or parental education. In sum, we report a complex relation between convictions, treatment, and excess mortality among adolescents and young adults enrolled in specialized substance use treatment, signaling profound unmet clinical and social work needs.
Keywords
Substance use treatment, Adolescents, Young adults, Mortality, Sweden
National Category
Social Work
Research subject
Social Work
Identifiers
urn:nbn:se:su:diva-258055 (URN)10.1186/s13034-026-01125-1 (DOI)001807566300001 ()2-s2.0-105043457255 (Scopus ID)
Funder
Stockholm UniversityForte, Swedish Research Council for Health, Working Life and Welfare, 2021-01726
2026-08-142026-08-142026-09-01Bibliographically approved