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Title [sv]
Parningstyp-kromosomen i askomycetsvampen Neurospora tetrasperma utgör en enkel modell för studier av evolutionen av könskromosomer
Title [en]
The mating-type chromosome of the filamentous ascomycete Neurospora tetrasperma represents a simple model for early sex chromosome evolution
Abstract [sv]
Sex chromosome evolution is assumed to take place by a gradual arrest of recombination between homologous autosomes, followed by a genetic decay of the non-recombining chromosome. The general model predicts that sex chromosome degeneration is aided by selective forces associated with two different sexes. However, the process is also affected by reduced recombination per se and a lower effective population size of sex chromosomes than autosomes. In addition, many model organisms have sex chromosomes where degeneration is nearly complete, and these retain few traces of the process leading to their degeneration. Here I propose a project to use the filamentous ascomycete Neurospora tetrasperma as a model to the evolution of sex chromosomes. Just as in many animals and plants, N. tetrasperma shows suppressed recombination and substantial divergence of the mating-type chromosome. However, it is hermaphroditic and therefore not exposed to sex specific selection pressure. In addition, its relative recent evolutionary origin makes it a suitable model for studies of the ongoing processes underlying early sex chromosome evolution. The objectives of this project is to use genomic data from natural and experimental populations of Neurospora to shed light on the following steps in the evolution of sex chromosomes: i) The mechanism of recombination suppression; ii) The increase in size of an existing recombination block; iii) The genetic degeneration of a non-recombining chromosomal region.
Principal InvestigatorJohannesson, Hanna
Coordinating organisation
Uppsala University
Funder
Period
2010-01-01 - 2012-12-31
Identifiers
DiVA, id: project:3636Project, id: 2009-05144_VR

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