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Objective Bayesian Meta-Analysis Based on Generalized Marginal Multivariate Random Effects Model
Stockholms universitet, Naturvetenskapliga fakulteten, Matematiska institutionen.ORCID-id: 0000-0001-7855-8221
Antal upphovsmän: 22024 (Engelska)Ingår i: Bayesian Analysis, ISSN 1936-0975, E-ISSN 1931-6690, Vol. 19, nr 2, s. 531-564Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Objective Bayesian inference procedures are derived for the parameters of the multivariate random effects model generalized to elliptically contoured distributions. The posterior for the overall mean vector and the between -study covariance matrix is deduced by assigning two noninformative priors to the model parameter, namely the Berger and Bernardo reference prior and the Jeffreys prior, whose analytical expressions are obtained under weak distributional assumptions. It is shown that the only condition needed for the posterior to be proper is that the sample size is larger than the dimension of the data -generating model, independently of the class of elliptically contoured distributions used in the definition of the generalized multivariate random effects model. The theoretical findings of the paper are applied to real data consisting of ten studies about the effectiveness of hypertension treatment for reducing blood pressure where the treatment effects on both the systolic blood pressure and diastolic blood pressure are investigated. MSC2020 subject classifications: Primary 62F15, 62H10; secondary 62H12.

Ort, förlag, år, upplaga, sidor
2024. Vol. 19, nr 2, s. 531-564
Nyckelord [en]
multivariate random effects model, noninformative prior, propriety, elliptically contoured distribution, multivariate meta-analysis
Nationell ämneskategori
Beräkningsmatematik
Identifikatorer
URN: urn:nbn:se:su:diva-228994DOI: 10.1214/23-BA1363ISI: 001203880900006Scopus ID: 2-s2.0-85190840090OAI: oai:DiVA.org:su-228994DiVA, id: diva2:1856731
Tillgänglig från: 2024-05-07 Skapad: 2024-05-07 Senast uppdaterad: 2024-11-14Bibliografiskt granskad

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