There is growing concern about the unprecedented rise in international seafood trade that relies on increasingly overused and climate-driven fisheries. Seafood trade relations, the multi-dimensional relations between fishers, traders, and countries for seafood exchange and other interactions, are central in the process of globalization. Despite empirical evidence of their importance, (bio-)economic models that inform fisheries management usually reduce trade relations to price dynamics. Here, I aim to understand better the role of seafood trade relations for models that guide the sustainable and equitable management of globalizing fisheries. I studied traders' collusion in Mexico (Paper I), fisher-trader relations in Indonesia (Paper II), countries trade relations in a global network study (Paper III), and fisher-market relations in a theoretical model (Paper IV). I demonstrate that seafood trade relations are affected by social-ecological change (SEC), such as climate change. Their responses, in turn, influence how other fishery actors, such as fishers, are affected. Together these interactions shape the importance of seafood trade relations to SEC. These insights suggest that seafood trade emerges from, interacts, and co-evolves with seafood trade relations across scales, which needs to be represented in management models that analyze the 'interplay of seafood trade relations with globalizing fisheries'.