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Sustainable and scalable one-pot synthesis of diaryliodonium salts
Stockholm University, Faculty of Science, Department of Organic Chemistry. Stockholm University, Faculty of Science, Department of Chemistry, Stockholm University Center for Circular and Sustainable Systems (SUCCeSS).ORCID iD: 0000-0002-6402-1391
Stockholm University, Faculty of Science, Department of Organic Chemistry.
Stockholm University, Faculty of Science, Department of Organic Chemistry.
Stockholm University, Faculty of Science, Department of Organic Chemistry.
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Number of Authors: 52025 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 61, no 27, p. 5158-5161Article in journal (Refereed) Published
Abstract [en]

Two one-pot routes from iodoarenes to diaryliodonium triflates have been developed in the sustainable solvent ethyl acetate. The first method yields the recently reported aryl(dimethylisoxazolyl)iodonium triflates, circumventing the need for stepwise synthesis of this chemoselective arylating reagent. The second method gives other types of diaryliodonium salts, and the scalability of the protocols was exhibited with two >45 mmol scale-ups with impressively low E-factors.

Place, publisher, year, edition, pages
2025. Vol. 61, no 27, p. 5158-5161
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Organic Chemistry
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URN: urn:nbn:se:su:diva-241916DOI: 10.1039/d5cc00774gISI: 001441423200001PubMedID: 40067736Scopus ID: 2-s2.0-105000147286OAI: oai:DiVA.org:su-241916DiVA, id: diva2:1951276
Available from: 2025-04-10 Created: 2025-04-10 Last updated: 2025-10-01Bibliographically approved

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Doobary, SayadVillo, PiretOlofsson, Berit

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