Positive youth development (PYD) has gained considerable traction among developmental scientists, but past studies were generally conducted among youth samples from Minority World countries. This study investigated the factorial validity of the newly developed 7Cs model of PYD (competence, confidence, connection, character, caring, contribution, and creativity). Specifically, we compared four measurement models (one-factor, seven-factor, higher order, and bifactor) among emerging adults living in five Southeast Asian countries. The study also aimed to establish evidence of measurement invariance across gender, age, education, and country of origin. Criterion-related validity was also sought using COVID-19 socially responsive behaviors and anxiety. Controlling for the influence of gender, age, and education, sample-level comparisons were also performed on the 7Cs. Data came from 1,888 emerging adults (M_age = 24.10; SD_age = 6.89) from Indonesia (n = 253), Malaysia (n = 289), the Philippines (n = 496), Singapore (n = 306), and Thailand (n = 544) during the pandemic. The results supported the superiority of the seven-factor model, which exhibited strict invariance across gender, age, and education and partial scalar invariance across country of origin. The 7Cs exhibited mixed associations with the pandemic-related measures. Significant differences were found in the 7Cs across the five countries. The study provides additional evidence on the theoretical validity of the 7Cs model among youth from understudied settings, while also highlighting avenues for refining current PYD measures.