The advancement of wearable intelligent systems presents a unique opportunity to transform how humans interact with digital content. This workshop explores the design of Interactive Multimodal Information Retrieval and Access systems specifically tailored for Heads-Up Computing environments. By leveraging multimodal inputs, such as voice, gaze, and gesture, these systems enable real-time, hands-free access to digital information, facilitating seamless and efficient interaction. The goal is to support tasks requiring rapid information access in dynamic environments while ensuring users remain”heads-up” and engaged with the real world. This half-day workshop will share research outcomes and best practices, foster community building, and facilitate discussions on key challenges. By bringing together researchers and practitioners, it aims to drive further advancements in both research and practical applications within this rapidly evolving field.