We argue that a seismic shift in the landscape of per- and polyfluoroalkyl substances (PFAS) uses can be observed. From conversations with representatives of the fluorochemical industry and of large brands of consumer products; from recent statements made in the general discussion among industry, consumer groups, environmental NGOs, and academic scientists; from various analyses of the availability of alternatives to PFASs in many use areas, including our own work; (1−4) and from the decision of a major PFAS manufacturer (3M) to leave entirely the production of PFAS, (5) we conclude that in many PFAS use areas, the transition to nonfluorinated alternatives is underway and is gaining more and more momentum.

The ongoing transition to PFAS-free alternatives includes uses such as surface treatment for a wide range of materials (food-contact materials, textiles, carpets, leather, metals, and cookware), lubrication, personal care products and cosmetics, firefighting foams, components of electrical devices (e.g., in fuel cells), ski waxes, cleaning products, building materials, refrigerants, and many other uses not highlighted here.