Introduction: Globally, access to evidence-based psychological treatments is limited, but virtual and augmented reality (XR) offer scalable solutions. This presentation overviews the evidence base for XR cognitive behavioral therapy (CBT) in treating Specific Phobia and Obsessive-Compulsive Disorder (OCD). Specifically, I will present three VR/AR studies on specific phobia (ZeroPhobia) and introduce an ongoing AR study for OCD targeting contamination fears (ZeroOCD).

Methods: The broader evidence base supporting XR interventions will be reviewed, followed by a discussion of three single-blind randomized clinical trials evaluating the ZeroPhobia program. These trials compared a self-guided XR CBT app with a wait-list control among Dutch participants (aged 18–65) with acrophobia, aviophobia, or arachnophobia. The intervention comprised six animated modules and gamified XR environments delivered over a three- to six-week period.

Results: Current evidence supports VR/AR treatments, including self-guided XR-CBT, as effective for specific phobias—producing significant, lasting symptom reductions and serving as an alternative to traditional therapy. For OCD, AR treatments for contamination fears are in early stages but show promise. ZeroPhobia trials demonstrated significant symptom reductions with large effect sizes (d = 0.98–1.29), maintained at both 3- and 12-month follow-ups.

Conclusions: Preliminary findings suggest that low-cost, self-guided XR CBT can effectively reduce phobic symptoms and improve accessibility to evidence-based care. Although AR-based interventions for OCD remain emerging, early studies indicate they may offer an effective, accessible alternative to intensive traditional therapies, warranting further investigation.